Actor and stuntman Johnny Knoxville served as ESPN’s College Gameday celebrity guest picker on Saturday, October 5, during a broadcast in Knoxville, Tennessee. The segment included Knoxville’s selections for several matchups, accompanied by lighthearted and humorous commentary directed at panelists and coaches.
Knoxville’s remarks included a wager tied to his prediction for the Missouri vs. Mississippi State game. He stated, “I'm so sure about this game, that if Missouri loses, I will punish myself by listening to Pat McAfee's new album on repeat until Halloween.” McAfee, a panelist on the show, responded with laughter, and Knoxville added, “No offense.”
During the Georgia vs. Oklahoma selection, Knoxville compared the teams to medical conditions, saying, “I'm from Knoxville so this is like rooting for the gout versus the syphilis. I'm going with the gout. I'll take Georgia.” The remark drew visible reactions from McAfee and fellow panelist Chris Herbstreit, who appeared to react with surprise.
Knoxville also addressed LSU head coach Lane Kiffin in his pick for the LSU vs. Texas A&M game, stating, “I don't know how anyone can root for Lane 'Left Out in the Parking Lot' Kiffin. He is to college football what toe fungus is.”
The broadcast took place ahead of the Missouri vs. Mississippi State game, which was one of several SEC matchups that weekend. Both teams entered the contest undefeated, with Missouri ranked No. 19 and Mississippi State ranked No. 24 in the AP Poll. Mississippi State won the game 31-24.
Knoxville’s selections and remarks were part of the show’s recurring “guest picker” segment, which often features comedic or unconventional takes from celebrity guests.